Conjunctival Melanoma Angiotropic Microsatellitosis: A Mechanism of Local Extravascular Migratory Metastasis
نویسندگان
چکیده
منابع مشابه
Satellite in transit metastases in rapidly fatal conjunctival melanoma: implications for angiotropism and extravascular migratory metastasis (description of a murine model for conjunctival melanoma).
Little information is currently available concerning loco-regional metastases such as satellite and in transit metastases and their natural history in conjunctival melanoma as compared to cutaneous melanoma. Angiotropism, a marker of extravascular migration of melanoma cells along vascular channels, often appears responsible for microscopic satellite, satellite and in transit metastases develop...
متن کاملScreening for conjunctival melanoma metastasis: literature review.
Local tumour control in conjunctival melanoma has improved in recent years. However the tumour-related death rate of these patients is still 14% at 5 years up to 33% at 15 years. With the introduction of sentinel node biopsies for conjunctival melanomas with a poor prognosis and screening for locoregional and distant metasases prognosis might be improved.
متن کاملA case of conjunctival malignant melanoma with local recurrence.
Malignant melanoma of the conjunctiva is a rare tumour of middle and old age. It is seen predominantly in whites, and is rare in those of pigmented ethnicity. Its clinical presentation varies, and making a clinical diagnosis may be difficult. The tumour is potentially fatal and displays a high rate of recurrence, which can be attributed to delay in diagnosis, as well as inadequate surgical appr...
متن کاملRetrograde metastasis of cutaneous melanoma to conjunctival lymphatics.
Report of a Case. A 61-year-old man developed cutaneous melanoma in the right preauricular skin. It was managed by surgical resections, skin grafts, irradiation, chemotherapy, and laser for local recurrences and cervical node metastasis. After 18 months, he was referred for progressive ipsilateral conjunctival pigmentation. Examination disclosed cutaneous pigmentation and scarring in the right ...
متن کاملConjunctival Melanoma in Chinese Patients: Local Recurrence, Metastasis, Mortality, and Comparisons With Caucasian Patients.
Purpose To evaluate the prognosis in Chinese patients with conjunctival melanoma and determine its predictors. Further, to explore the racial differences in clinical characteristics and outcomes between Chinese and Caucasian patients. Methods This cohort study included 57 eyes of 57 consecutive patients with pathologically verified conjunctival melanoma between 1996 and 2016. Medical records ...
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ژورنال
عنوان ژورنال: Ocular Oncology and Pathology
سال: 2020
ISSN: 2296-4681,2296-4657
DOI: 10.1159/000505270